Spider-Man's dream of joining the Avengers becomes a nightmare when Loki switches bodies with the web-slinger, turning his new teammates against him. In part two, Spider-Man and his friends team up with the Avengers to stop Loki and Doctor Octopus from destroying New York City with an army of Ven...
After a case of mistaken identity caused by Loki and Doctor Octopus, Spider-Man must convince his old team that he's the real Spider-Man before he is destroyed by the Avengers and before Loki's plot is furthered.
Spider-Man and Dr. Strange attempt to help the super-powered runaways Cloak & Dagger, but the mystical Dormammu has other plans.
Spidey's patience is tested when his old academic rival Amadeus Cho is recruited into S.H.I.E.L.D.
Spider-Man tries to track down a mysterious thief known as The Vulture, a young man who can't remember his past.
Spider-Man's newly assembled team of teen heroes is put to the test when Taskmaster puts his master plan into action.
When the Goblin opens portals to alternate worlds, Spider-Man teams up with alternate versions of Spider-Man to stop him, including Spider-Man Noir and Spider-Ham.
Spider-Man chases Goblin through a portal to Medieval York, where he meets Spyder-Knight, and then to a parallel universe where Peter Parker has died and 13-year-old Miles Morales is now Spider-Man.
When the Goblin uses DNA from six alternative Spider-Men to grow his own powers, the original Spider-Man assembles his alternative world counterparts to defeat him.
Grandmaster has won the Contest of Champions and takes the city as a reward, but Spider-Man asks for a winner-take-all rematch in which the Collector must play the most crucial part of all.