Recently dumped by his girlfriend, slacker Rell (Jordan Peele) finds some happiness when a cute kitten winds up on his doorstep. After a heartless thief steals the cat, Rell recruits his cousin Clarence (Keegan-Michael Key) to help him retrieve it. They soon learn that a thug named Cheddar (Method Man) has the animal, and he'll only give it back if the two men agree to work for him. Armed with guns and a gangster attitude, it doesn't take long for the hapless duo to land in big trouble.